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| Cat.No | ACP16601 | Target Name | FRMPD2 |
|---|---|---|---|
| Target Synonyms | FRMPD2; PDZD5C; PDZK4; PDZK5C; FERM and PDZ domain-containing protein 2; PDZ domain-containing protein 4; PDZ domain-containing protein 5C | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q68DX3 |
|---|
Uniprot Id
Q68DX3
Target Species
Human
Target Name
FRMPD2
Target Full Name
FERM and PDZ domain-containing protein 2
Target Function
May play a role in the regulation of tight junction formation. Binds phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2).
Target Subcellular Location
Cytoplasm. Basolateral cell membrane. Cell junction, tight junction. Note=Colocalizes with CTNNB1, CDH1 and PKP4 at the basolateral membrane. Colocalizes with TJP1 at tight junctions. Its recruitment to cell-cell contacts requires CDH1.
Target Tissue Specificity
Expressed in epithelial cells.
Target Synonyms
FRMPD2; PDZD5C; PDZK4; PDZK5C; FERM and PDZ domain-containing protein 2; PDZ domain-containing protein 4; PDZ domain-containing protein 5C
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