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Recombinant Human Fibroblast growth factor 9 (FGF9)

ACP23543

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP23543 Target NameFGF9
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range4-208Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP31371
Background Information
  • Uniprot Id

    P31371

  • Target Species

    Human

  • Target Name

    FGF9

  • Target Full Name

    Fibroblast growth factor 9

  • Target Function

    Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. May have a role in glial cell growth and differentiation during development, gliosis during repair and regeneration of brain tissue after damage, differentiation and survival of neuronal cells, and growth stimulation of glial tumors.

  • Target Involvement

    Multiple synostoses syndrome 3 (SYNS3)

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Heparin-binding growth factors family

  • Target Tissue Specificity

    Glial cells.

  • Target Synonyms

    FGF 9; FGF-9; FGF9; FGF9_HUMAN; Fibroblast growth factor 9; GAF (Glia-activafibroblast growth factor 9 (glia-activating factor); GAF; Glia Activating Factor; Glia-activating factor; HBFG 9; HBFG9; HBGF-9; Heparin-binding growth factor 9; MGC119914; MGC119915; SYNS3

  • Target Background

    The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.

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