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Recombinant Human Forkhead box protein E1 (FOXE1)

ACP21598

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP21598 Target NameFOXE1
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-373Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO00358
Background Information
  • Uniprot Id

    O00358

  • Target Species

    Human

  • Target Name

    FOXE1

  • Target Full Name

    Forkhead box protein E1

  • Target Function

    Transcription factor that binds consensus sites on a variety of gene promoters and activate their transcription. Involved in proper palate formation, most probably through the expression of MSX1 and TGFB3 genes which are direct targets of this transcription factor. Also implicated in thyroid gland morphogenesis. May indirectly play a role in cell growth and migration through the regulation of WNT5A expression.

  • Target Involvement

    Bamforth-Lazarus syndrome (BLS); Thyroid cancer, non-medullary, 4 (NMTC4)

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Detected in adult brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, heart, colon, small intestine testis and thymus. Expression was strongest in heart and pancreas.

  • Target Synonyms

    FKH L15; FKHL 15; FKHL15; Forkhead (Drosophila) like 15; Forkhead box E1; Forkhead box E2; Forkhead box protein E1; Forkhead box protein E2; Forkhead drosophila homolog like 15; Forkhead like 15; Forkhead related protein FKHL 15; Forkhead related protein FKHL15; Forkhead-related protein FKHL15; FOX E1; FOX E2; FOXE 1; FOXE 2; FOXE1; FOXE1_HUMAN; FOXE2; HFKH 4; HFKH4; HFKL 5; HFKL5; HNF-3/fork head-like protein 5; Thyroid transcription factor 2; TITF 2; TITF2; TTF 2; TTF-2; TTF2

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