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Dive into the study of Forkhead box protein M1 (FOXM1), a crucial transcription factor implicated in cell cycle regulation and cell proliferation, with our Recombinant Human FOXM1 protein. FOXM1, encoded by the FOXM1 gene, is a key player in the regulation of various cellular processes, including DNA damage response, angiogenesis, and metastasis, making it an essential focus in cancer research. Our Recombinant Human FOXM1 protein is expressed in an E.coli system and covers the 235-327aa region of the full-length protein. The N-terminal 10xHis-SUMO-tag and C-terminal Myc-tag facilitate efficient protein purification and detection in your experimental setup. This high-quality, partial-length FOXM1 protein boasts a purity greater than 90%, as validated by SDS-PAGE, providing you with a dependable research tool. Choose between liquid or lyophilized powder forms according to your laboratory needs and streamline your research endeavors.
Dive into the study of Forkhead box protein M1 (FOXM1), a crucial transcription factor implicated in cell cycle regulation and cell proliferation, with our Recombinant Human FOXM1 protein. FOXM1, encoded by the FOXM1 gene, is a key player in the regulation of various cellular processes, including DNA damage response, angiogenesis, and metastasis, making it an essential focus in cancer research.
Our Recombinant Human FOXM1 protein is expressed in an E.coli system and covers the 235-327aa region of the full-length protein. The N-terminal 10xHis-SUMO-tag and C-terminal Myc-tag facilitate efficient protein purification and detection in your experimental setup. This high-quality, partial-length FOXM1 protein boasts a purity greater than 90%, as validated by SDS-PAGE, providing you with a dependable research tool. Choose between liquid or lyophilized powder forms according to your laboratory needs and streamline your research endeavors.
| Cat.No | ACP02266 | Target Name | FOXM1 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 235-327aa | Mol Weight | 31.2kDa |
| Protein Length | Partial | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q08050 |
|---|
Uniprot Id
Q08050
Target Species
Human
Target Name
FOXM1
Target Full Name
Forkhead box protein M1
Target Function
Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not e
Target Research Area
Others
Target Synonyms
FKHL16; Forkhead box M1; Forkhead box protein M1; forkhead like 16; Forkhead-related protein FKHL16; FOX M1; Foxm1; FOXM1_HUMAN; FOXM1B; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HFH11; HNF-3/fork-head homolog 11; HNF3; INS1; M phase phosphoprotein 2; M-phase phosphoprotein 2; MPHOSPH2; MPM-2 reactive phosphoprotein 2; MPP2; PIG29; TGT3; Transcription factor Trident; Trident; WIN; Winged-helix factor from INS-1 cells; Winged-helix factor from INS1 cells
Target Background
The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene.
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