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Recombinant Human Forkhead box protein M1 (FOxM1), Truncated

Dive into the study of Forkhead box protein M1 (FOXM1), a crucial transcription factor implicated in cell cycle regulation and cell proliferation, with our Recombinant Human FOXM1 protein. FOXM1, encoded by the FOXM1 gene, is a key player in the regulation of various cellular processes, including DNA damage response, angiogenesis, and metastasis, making it an essential focus in cancer research. Our Recombinant Human FOXM1 protein is expressed in an E.coli system and covers the 235-327aa region of the full-length protein. The N-terminal 10xHis-SUMO-tag and C-terminal Myc-tag facilitate efficient protein purification and detection in your experimental setup. This high-quality, partial-length FOXM1 protein boasts a purity greater than 90%, as validated by SDS-PAGE, providing you with a dependable research tool. Choose between liquid or lyophilized powder forms according to your laboratory needs and streamline your research endeavors.

ACP02266

Dive into the study of Forkhead box protein M1 (FOXM1), a crucial transcription factor implicated in cell cycle regulation and cell proliferation, with our Recombinant Human FOXM1 protein. FOXM1, encoded by the FOXM1 gene, is a key player in the regulation of various cellular processes, including DNA damage response, angiogenesis, and metastasis, making it an essential focus in cancer research.
Our Recombinant Human FOXM1 protein is expressed in an E.coli system and covers the 235-327aa region of the full-length protein. The N-terminal 10xHis-SUMO-tag and C-terminal Myc-tag facilitate efficient protein purification and detection in your experimental setup. This high-quality, partial-length FOXM1 protein boasts a purity greater than 90%, as validated by SDS-PAGE, providing you with a dependable research tool. Choose between liquid or lyophilized powder forms according to your laboratory needs and streamline your research endeavors.

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Specifications


Cat.No ACP02266 Target NameFOXM1
FormLiquid or Lyophilized powderExpression SystemE.coli
Expression Range235-327aaMol Weight31.2kDa
Protein LengthPartialPurityGreater than 90% as determined by SDS-PAGE.
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ08050
Background Information
  • Uniprot Id

    Q08050

  • Target Species

    Human

  • Target Name

    FOXM1

  • Target Full Name

    Forkhead box protein M1

  • Target Function

    Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Expressed in thymus, testis, small intestine, colon followed by ovary. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not e

  • Target Research Area

    Others

  • Target Synonyms

    FKHL16; Forkhead box M1; Forkhead box protein M1; forkhead like 16; Forkhead-related protein FKHL16; FOX M1; Foxm1; FOXM1_HUMAN; FOXM1B; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HFH11; HNF-3/fork-head homolog 11; HNF3; INS1; M phase phosphoprotein 2; M-phase phosphoprotein 2; MPHOSPH2; MPM-2 reactive phosphoprotein 2; MPP2; PIG29; TGT3; Transcription factor Trident; Trident; WIN; Winged-helix factor from INS-1 cells; Winged-helix factor from INS1 cells

  • Target Background

    The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene.

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