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| Cat.No | ACP15656 | Target Name | FGD2 |
|---|---|---|---|
| Target Synonyms | FGD2; ZFYVE4FYVE; RhoGEF and PH domain-containing protein 2; Zinc finger FYVE domain-containing protein 4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-655 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q7Z6J4 |
|---|
Uniprot Id
Q7Z6J4
Target Species
Human
Target Name
FGD2
Target Full Name
FYVE, RhoGEF and PH domain-containing protein 2
Target Function
Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm. Nucleus. Early endosome. Early endosome membrane. Cell projection, ruffle membrane.
Target Synonyms
FGD2; ZFYVE4FYVE; RhoGEF and PH domain-containing protein 2; Zinc finger FYVE domain-containing protein 4
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