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Recombinant Human G2/M phase-specific E3 ubiquitin-protein ligase (G2E3)

ACP16495

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16495 Target NameG2E3
Target SynonymsG2E3; KIAA1333G2/M phase-specific E3 ubiquitin-protein ligase; EC 2.3.2.26; G2/M phase-specific HECT-type E3 ubiquitin transferaseFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-706
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ7L622
Background Information
  • Uniprot Id

    Q7L622

  • Target Species

    Human

  • Target Name

    G2E3

  • Target Full Name

    G2/M phase-specific E3 ubiquitin-protein ligase

  • Target Function

    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Essential in early embryonic development to prevent apoptotic death.

  • Target Subcellular Location

    Nucleus, nucleolus. Cytoplasm.

  • Target Tissue Specificity

    Predominantly expressed in brain, liver, kidney, testes and ovary.

  • Target Synonyms

    G2E3; KIAA1333G2/M phase-specific E3 ubiquitin-protein ligase; EC 2.3.2.26; G2/M phase-specific HECT-type E3 ubiquitin transferase

  • Target Background

    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in apoptotic process and protein ubiquitination. Predicted to act upstream of or within blastocyst development; negative regulation of intrinsic apoptotic signaling pathway; and protein polyubiquitination. Located in Golgi apparatus and cytosol.

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