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Recombinant Human Gap junction alpha-5 protein (GJA5), Truncated

ACP06997

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP06997 Target NameGJA5
Target SynonymsGJA5; Gap junction alpha-5 protein; Connexin-40; Cx40FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP36382
Background Information
  • Uniprot Id

    P36382

  • Target Species

    Human

  • Target Name

    GJA5

  • Target Full Name

    Gap junction alpha-5 protein

  • Target Function

    One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

  • Target Involvement

    Atrial standstill 1 (ATRST1); Atrial fibrillation, familial, 11 (ATFB11)

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

  • Target Protein Families

    Connexin family, Alpha-type (group II) subfamily

  • Target Research Area

    Others

  • Target Synonyms

    GJA5; Gap junction alpha-5 protein; Connexin-40; Cx40

  • Target Background

    This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Mutations in this gene may be associated with atrial fibrillation. Alternatively spliced transcript variants encoding the same isoform have been described.

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