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| Cat.No | ACP03457 | Target Name | GATC |
|---|---|---|---|
| Target Synonyms | 15E1.2; gatC; GatC-like protein; GATCL_HUMAN; Glu AdT subunit C; Glutamyl tRNA(Gln) amidotransferase subunit C mitochondrial; Protein 15E1.2 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-136aa |
| Mol Weight | 42.1kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O43716 |
|---|
Uniprot Id
O43716
Target Species
Human
Target Name
GATC
Target Full Name
Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial
Target Function
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).
Target Subcellular Location
Mitochondrion.
Target Protein Families
GatC family
Target Research Area
others
Target Synonyms
15E1.2; gatC; GatC-like protein; GATCL_HUMAN; Glu AdT subunit C; Glutamyl tRNA(Gln) amidotransferase subunit C mitochondrial; Protein 15E1.2
Target Background
Enables glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity. Involved in glutaminyl-tRNAGln biosynthesis via transamidation and mitochondrial translation. Located in mitochondrion. Part of glutamyl-tRNA(Gln) amidotransferase complex. Implicated in combined oxidative phosphorylation deficiency 42.
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