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| Cat.No | ACP15648 | Target Name | GLRX5 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 32-157 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86SX6 |
|---|
Uniprot Id
Q86SX6
Target Species
Human
Target Name
GLRX5
Target Full Name
Glutaredoxin-related protein 5, mitochondrial
Target Function
Monothiol glutaredoxin involved in mitochondrial iron-sulfur (Fe/S) cluster transfer. Receives 2Fe/2S clusters from scaffold protein ISCU and mediates their transfer to apoproteins, to the 4Fe/FS cluster biosynthesis machinery, or export from mitochondrion. Required for normal regulation of hemoglobin synthesis by the iron-sulfur protein ACO1.
Target Involvement
Anemia, sideroblastic, 3, pyridoxine-refractory (SIDBA3); Spasticity, childhood-onset, with hyperglycinemia (SPAHGC)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Glutaredoxin family, Monothiol subfamily
Target Synonyms
C14orf87; Chromosome 14 open reading frame 87; FLB4739; GLRX 5; Glrx5; GLRX5_HUMAN; Glutaredoxin 5 homolog; Glutaredoxin related protein 5; Glutaredoxin-related protein 5; Glutaredoxin5; GRX5; MGC14129; mitochondrial; Monothiol glutaredoxin-5; PRO1238
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