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| Cat.No | ACP19411 | Target Name | GPX7 |
|---|---|---|---|
| Target Synonyms | CL683; FLJ14777; Glutathione peroxidase 7; GPx-7; GPX6; GPX7; GPX7_HUMAN; GSHPx-7; NPGPx | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 20-187 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96SL4 |
|---|
Uniprot Id
Q96SL4
Target Species
Human
Target Name
GPX7
Target Full Name
Glutathione peroxidase 7
Target Function
It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.
Target Involvement
Barrett esophagus (BE)
Target Subcellular Location
Secreted.
Target Protein Families
Glutathione peroxidase family
Target Tissue Specificity
Expressed in esophageal epithelial cells; expression is up-regulated after exposure to acidic bile acids.
Target Synonyms
CL683; FLJ14777; Glutathione peroxidase 7; GPx-7; GPX6; GPX7; GPX7_HUMAN; GSHPx-7; NPGPx
Target Background
Enables catalase activity. Predicted to be involved in cellular response to oxidative stress. Located in endoplasmic reticulum.
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