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| Cat.No | ACP20884 | Target Name | GPC4 |
|---|---|---|---|
| Target Synonyms | dJ900E8.1 glypican 4; Glypican proteoglycan 4; Gpc4; GPC4_HUMAN; K Glypican; K-glypican; Kglypican; OTTHUMP00000024052; Secreted glypican 4; Secreted glypican-4; UNQ474/PRO937 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 19-529 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75487 |
|---|
Uniprot Id
O75487
Target Species
Human
Target Name
GPC4
Target Full Name
Glypican-4
Target Function
Cell surface proteoglycan that bears heparan sulfate. May be involved in the development of kidney tubules and of the central nervous system.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.; [Secreted glypican-4]: Secreted, extracellular space.
Target Protein Families
Glypican family
Target Synonyms
dJ900E8.1 glypican 4; Glypican proteoglycan 4; Gpc4; GPC4_HUMAN; K Glypican; K-glypican; Kglypican; OTTHUMP00000024052; Secreted glypican 4; Secreted glypican-4; UNQ474/PRO937
Target Background
Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome.
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