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| Cat.No | ACP04110 | Target Name | GMPR |
|---|---|---|---|
| Target Synonyms | GMPR; GMPR1GMP reductase 1; GMPR 1; EC 1.7.1.7; Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase 1 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-345aa |
| Mol Weight | 53.4kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P36959 |
|---|
Uniprot Id
P36959
Target Species
Human
Target Name
GMPR
Target Full Name
GMP reductase 1
Target Function
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
Target Protein Families
IMPDH/GMPR family, GuaC type 1 subfamily
Target Research Area
Cell Biology
Target Synonyms
GMPR; GMPR1GMP reductase 1; GMPR 1; EC 1.7.1.7; Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase 1
Target Background
This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.
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