Home Products Recombinant Human Group XIIA secretory phospholipase A2 (PLA2G12A)

Recombinant Human Group XIIA secretory phospholipase A2 (PLA2G12A)

ACP05178

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Specifications

Cat.No	ACP05178	Target Name	PLA2G12A
Form	Liquid or Lyophilized powder	Expression System	E.coli
Expression Range	23-189aa	Mol Weight	26.2 kDa
Protein Length	Full Length of Mature Protein	Purity	Greater than 85% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BZM1

Background Information

Uniprot Id

Q9BZM1
Target Species

Human
Target Name

PLA2G12A
Target Full Name

Group XIIA secretory phospholipase A2
Target Function

PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Does not exhibit detectable activity toward sn-2-arachidonoyl- or linoleoyl-phosphatidylcholine or -phosphatidylethanolamine.
Target Subcellular Location

Secreted. Cytoplasm.
Target Protein Families

Phospholipase A2 family
Target Tissue Specificity

Abundantly expressed in heart, skeletal muscle, kidney, liver and pancreas.
Target Research Area

Cardiovascular, Metabolism
Target Synonyms

EC 3.1.1.4 ; Group XII secreted phospholipase A2; Group XIIA secreted phospholipase A2; Group XIIA secretory phospholipase A2; Group XIIA secretory phospholipase A2 precursor ; GXII; GXII sPLA2; PG12A_HUMAN; phosphatidylcholine 2 acylhydrolase 12A; Phosphatidylcholine 2 acylhydrolase GXII ; Phosphatidylcholine 2-acylhydrolase 12A; Phospholipase A2 group XIIA; PLA2G12 ; Pla2g12a; ROSSY; sPLA2 XII; sPLA2-XII
Target Background

Secreted phospholipase A2 (sPLA2) enzymes liberate arachidonic acid from phospholipids for production of eicosanoids and exert a variety of physiologic and pathologic effects. Group XII sPLA2s, such as PLA2G12A, have relatively low specific activity and are structurally and functionally distinct from other sPLA2s (Gelb et al., 2000 [PubMed 11031251]).

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Recombinant Human Group XIIA secretory phospholipase A2 (PLA2G12A)

Specifications

Immunogen Information

Inquire Recombinant Human Group XIIA secretory phospholipase A2 (PLA2G12A) Now

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