Home Products Recombinant Human Growth arrest-specific protein 2 (GAS2)

Recombinant Human Growth arrest-specific protein 2 (GAS2)

ACP21348

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Specifications

Cat.No	ACP21348	Target Name	GAS2
Target Synonyms	GAS 2; GAS-2; Gas2; GAS2_HUMAN; Growth arrest specific 2; Growth arrest specific protein 2; Growth arrest-specific protein 2; MGC32610	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-313
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O43903

Background Information

Uniprot Id

O43903
Target Species

Human
Target Name

GAS2
Target Full Name

Growth arrest-specific protein 2
Target Function

May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process.
Target Subcellular Location

Cytoplasm, cytoskeleton, stress fiber. Membrane; Peripheral membrane protein.
Target Protein Families

GAS2 family
Target Tissue Specificity

Ubiquitously expressed with highest levels in liver, lung, and kidney. Not found in spleen.
Target Synonyms

GAS 2; GAS-2; Gas2; GAS2_HUMAN; Growth arrest specific 2; Growth arrest specific protein 2; Growth arrest-specific protein 2; MGC32610
Target Background

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants.

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Recombinant Human Growth arrest-specific protein 2 (GAS2)

Specifications

Immunogen Information

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