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| Cat.No | ACP23745 | Target Name | GCHFR |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-84 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P30047 |
|---|
Uniprot Id
P30047
Target Species
Human
Target Name
GCHFR
Target Full Name
GTP cyclohydrolase 1 feedback regulatory protein
Target Function
Mediates tetrahydrobiopterin inhibition of GTP cyclohydrolase 1. This inhibition is reversed by L-phenylalanine.
Target Subcellular Location
Nucleus. Nucleus membrane. Cytoplasm, cytosol.
Target Protein Families
GFRP family
Target Tissue Specificity
In epidermis, expressed predominantly in basal undifferentiated keratinocytes and in some but not all melanocytes (at protein level).
Target Synonyms
GCHFR; GFRP; GFRP_HUMAN; GTP cyclohydrolase 1 feedback regulatory protein; GTP cyclohydrolase I feedback regulator; GTP cyclohydrolase I feedback regulatory protein; HsT16933; MGC138467; MGC138469; p35
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