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| Cat.No | ACP12909 | Target Name | NAF1 |
|---|---|---|---|
| Target Synonyms | NAF1; H/ACA ribonucleoprotein complex non-core subunit NAF1; hNAF1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-494 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96HR8 |
|---|
Uniprot Id
Q96HR8
Target Species
Human
Target Name
NAF1
Target Full Name
H/ACA ribonucleoprotein complex non-core subunit NAF1
Target Function
RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
NAF1 family
Target Synonyms
NAF1; H/ACA ribonucleoprotein complex non-core subunit NAF1; hNAF1
Target Background
Enables identical protein binding activity and telomerase RNA binding activity. Involved in regulation of nucleobase-containing compound metabolic process; ribosome biogenesis; and telomerase holoenzyme complex assembly. Located in nucleoplasm. Part of sno(s)RNA-containing ribonucleoprotein complex.
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