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| Cat.No | ACP10187 | Target Name | HSPB7 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-170 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UBY9 |
|---|
Uniprot Id
Q9UBY9
Target Species
Human
Target Name
HSPB7
Target Full Name
Heat shock protein beta-7
Target Subcellular Location
Cytoplasm. Nucleus. Nucleus, Cajal body. Note=Resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
Target Protein Families
Small heat shock protein (HSP20) family
Target Tissue Specificity
Isoform 1 is highly expressed in adult and fetal heart, skeletal muscle, and at a much lower levels in adipose tissue and in aorta. Undetectable in other tissues. Isoform 2 and isoform 3 are poorly detected in heart.
Target Synonyms
Cardiovascular heat shock protein; cvHsp; DKFZp779D0968; FLJ32733; Heat shock 27kda protein family member 7; Heat shock protein beta 7; Heat shock protein beta-7; Hsp25 2; HspB7; HSPB7_HUMAN; Hypothetical protein flj34956; RP11-5P18.6
Target Background
This gene encodes a small heat shock family B member that can heterodimerize with similar heat shock proteins. Defects in this gene are associated with advanced heart failure. In addition, the encoded protein may be a tumor suppressor in the p53 pathway, with defects in this gene being associated with renal cell carcinoma.
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