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| Cat.No | ACP22377 | Target Name | HIST1H2BJ |
|---|---|---|---|
| Target Synonyms | H2BC11; H2BFR; HIST1H2BJ; Histone H2B type 1-J; Histone H2B.1; Histone H2B.r; H2B/r | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-126 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P06899 |
|---|
Uniprot Id
P06899
Target Species
Human
Target Name
H2BC11
Target Full Name
Histone H2B type 1-J
Target Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.; Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
Histone H2B family
Target Synonyms
H2BC11; H2BFR; HIST1H2BJ; Histone H2B type 1-J; Histone H2B.1; Histone H2B.r; H2B/r
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