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| Cat.No | ACP24003 | Target Name | EN2 |
|---|---|---|---|
| Target Synonyms | EN2; Homeobox protein engrailed-2; Homeobox protein en-2; Hu-En-2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-333 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P19622 |
|---|
Uniprot Id
P19622
Target Species
Human
Target Name
EN2
Target Full Name
Homeobox protein engrailed-2
Target Involvement
Genetic variations in EN2 may be associated with susceptibility to autism.
Target Subcellular Location
Nucleus.
Target Protein Families
Engrailed homeobox family
Target Synonyms
EN2; Homeobox protein engrailed-2; Homeobox protein en-2; Hu-En-2
Target Background
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
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