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| Cat.No | ACP10698 | Target Name | NKX6-2 |
|---|---|---|---|
| Target Synonyms | GTX; Homeobox protein NK-6 homolog B; Homeobox protein Nkx 6.2; Homeobox protein Nkx-6.2; MGC126684; NK6 homeobox 2; NK6 transcription factor related, locus 2; NKX6-2; NKX6.2; NKX62_HUMAN; NKX6B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-277 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9C056 |
|---|
Uniprot Id
Q9C056
Target Species
Human
Target Name
NKX6-2
Target Full Name
Homeobox protein Nkx-6.2
Target Function
Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'-(A/T)TTAATGA-3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions.
Target Involvement
Spastic ataxia 8, autosomal recessive, with hypomyelinating leukodystrophy (SPAX8)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Highest expression in brain.
Target Synonyms
GTX; Homeobox protein NK-6 homolog B; Homeobox protein Nkx 6.2; Homeobox protein Nkx-6.2; MGC126684; NK6 homeobox 2; NK6 transcription factor related, locus 2; NKX6-2; NKX6.2; NKX62_HUMAN; NKX6B
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