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Recombinant Human Homeobox protein Nkx-6.2 (NKX6-2)

ACP10698

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10698 Target NameNKX6-2
Target SynonymsGTX; Homeobox protein NK-6 homolog B; Homeobox protein Nkx 6.2; Homeobox protein Nkx-6.2; MGC126684; NK6 homeobox 2; NK6 transcription factor related, locus 2; NKX6-2; NKX6.2; NKX62_HUMAN; NKX6BFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-277
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9C056
Background Information
  • Uniprot Id

    Q9C056

  • Target Species

    Human

  • Target Name

    NKX6-2

  • Target Full Name

    Homeobox protein Nkx-6.2

  • Target Function

    Transcription factor with repressor activity involved in the regulation of axon-glial interactions at myelin paranodes in oligodendrocytes. Binds to the consensus DNA sequence 5'-(A/T)TTAATGA-3'. In oligodendrocytes, binds to MBP and PLP1 promoter regions.

  • Target Involvement

    Spastic ataxia 8, autosomal recessive, with hypomyelinating leukodystrophy (SPAX8)

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Highest expression in brain.

  • Target Synonyms

    GTX; Homeobox protein NK-6 homolog B; Homeobox protein Nkx 6.2; Homeobox protein Nkx-6.2; MGC126684; NK6 homeobox 2; NK6 transcription factor related, locus 2; NKX6-2; NKX6.2; NKX62_HUMAN; NKX6B

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