Recombinant Human Inhibin beta C chain (INHBC)

Uniprot Id

P55103

Target Species

Human

Target Name

INHBC

Target Full Name

Inhibin beta C chain

Target Function

Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

Target Subcellular Location

Secreted.

Target Protein Families

TGF-beta family

Target Tissue Specificity

Expressed in benign prostatic hyperplasia.

Target Research Area

Signal Transduction

Target Synonyms

Activin beta C chain; Activin beta-C chain; IHBC; Inhbc; INHBC_HUMAN; Inhibin beta C chain; Inhibin, beta C

Target Background

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate a subunit of homodimeric and heterodimeric activin complexes. The heterodimeric complex may function in the inhibition of activin A signaling. Transgenic mice overexpressing this gene exhibit defects in testis, liver and prostate.