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| Cat.No | ACP23494 | Target Name | ITPKA |
|---|---|---|---|
| Target Synonyms | 4, 5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A, ITPKA; Inositol-trisphosphate 3-kinase A; EC 2.7.1.127; Inositol 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-461 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P23677 |
|---|
Uniprot Id
P23677
Target Species
Human
Target Name
ITPKA
Target Full Name
Inositol-trisphosphate 3-kinase A
Target Synonyms
ITPKA; Inositol-trisphosphate 3-kinase A; EC 2.7.1.127; Inositol 1,4,5-trisphosphate 3-kinase A; IP3 3-kinase A; IP3K A; InsP 3-kinase A
Target Background
Regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins(1, 3, 4, 5)P4. The activity of the inositol 1, 4, 5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro.
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