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Recombinant Human Insulin-like growth factor-binding protein 6 (IGFBP6)

ACP23376

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Specifications

Cat.No	ACP23376	Target Name	IGFBP6
Target Synonyms	IBP 6; IBP-6; IBP6; IBP6_HUMAN; IGF binding protein 6; IGF-binding protein 6; IGFBP 6; IGFBP-6; IGFBP6; Insulin like growth factor binding protein 6; Insulin-like growth factor-binding protein 6	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	28-240
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P24592

Background Information

Uniprot Id

P24592
Target Species

Human
Target Name

IGFBP6
Target Full Name

Insulin-like growth factor-binding protein 6
Target Function

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration.
Target Subcellular Location

Secreted.
Target Synonyms

IBP 6; IBP-6; IBP6; IBP6_HUMAN; IGF binding protein 6; IGF-binding protein 6; IGFBP 6; IGFBP-6; IGFBP6; Insulin like growth factor binding protein 6; Insulin-like growth factor-binding protein 6
Target Background

Enables identical protein binding activity and insulin-like growth factor II binding activity. Involved in cell migration and positive regulation of stress-activated MAPK cascade. Part of insulin-like growth factor binary complex. Implicated in obesity. Biomarker of breast cancer; in situ carcinoma; leiomyoma; and neovascular inflammatory vitreoretinopathy.

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Recombinant Human Insulin-like growth factor-binding protein 6 (IGFBP6)

Specifications

Immunogen Information

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