Recombinant Human Interleukin-22 receptor subunit alpha-2 (IL22RA2)

Cat.No	ACP13253	Target Name	IL22RA2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	22-263	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP13253

Target Name

IL22RA2

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

22-263

Protein Length

Full Length of Mature Protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q969J5

Background Information

Uniprot Id

Q969J5
Target Species

Human
Target Name

IL22RA2
Target Full Name

Interleukin-22 receptor subunit alpha-2
Target Function

Isoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.; Isoform 1 may play a role in establishing and maintaining successful pregnancy.
Target Subcellular Location

Secreted.
Target Protein Families

Type II cytokine receptor family
Target Tissue Specificity

Expressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placen
Target Synonyms

IL 22BP; IL 22RA2; IL22RA2; Class II cytokine receptor; CRF2 10; CRF2 S1; CRF2-10; CRF2-S1; CRF2X; Cytokine receptor class II member 10; Cytokine receptor class-II member 10; Cytokine receptor family 2 member 10; Cytokine receptor family type 2; Cytokine receptor family type 2 soluble 1; I22R2_HUMAN; IL 22 receptor subunit alpha 2; IL 22R alpha 2; IL-22 receptor subunit alpha-2; IL-22BP; IL-22R-alpha-2; IL-22RA2; IL22 RA2; IL22BP; IL22R alpha 2; Il22ra2; Interleukin 22 binding protein; Interleukin 22 Receptor alpha 2; Interleukin-22 receptor subunit alpha-2; Interleukin-22-binding protein; MGC150509; MGC150510; soluble 1; ZcytoR16
Target Background

This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Recombinant Human Interleukin-22 receptor subunit alpha-2 (IL22RA2)

Specifications

Immunogen Information

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