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| Cat.No | ACP04155 | Target Name | KLK1 |
|---|---|---|---|
| Target Synonyms | Glandular kallikrein 1; hK 1; hK1; Kallikrein serine protease 1; Kallikrein-1; Kidney/pancreas/salivary gland kallikrein; Klk 6; KLK1; KLK1_HUMAN; Klk6; KLKR; Tissue kallikrein | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 25-262aa |
| Mol Weight | 42.4kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P06870 |
|---|
Uniprot Id
P06870
Target Species
Human
Target Name
KLK1
Target Full Name
Kallikrein-1
Target Function
Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Target Protein Families
Peptidase S1 family, Kallikrein subfamily
Target Tissue Specificity
Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84.
Target Research Area
Cancer
Target Synonyms
Glandular kallikrein 1; hK 1; hK1; Kallikrein serine protease 1; Kallikrein-1; Kidney/pancreas/salivary gland kallikrein; Klk 6; KLK1; KLK1_HUMAN; Klk6; KLKR; Tissue kallikrein
Target Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.
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