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| Cat.No | ACP12459 | Target Name | KRT12 |
|---|---|---|---|
| Target Synonyms | CK-12; Cytokeratin-12; K12; K1C12_HUMAN; Keratin 12; Keratin; Keratin; type I cytoskeletal 12; Keratin-12; KRT12; type I cytoskeletal 12 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-494 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q99456 |
|---|
Uniprot Id
Q99456
Target Species
Human
Target Name
KRT12
Target Full Name
Keratin, type I cytoskeletal 12
Target Function
Involved in corneal epithelium organization, integrity and corneal keratin expression.
Target Involvement
Corneal dystrophy, Meesmann (MECD)
Target Protein Families
Intermediate filament family
Target Tissue Specificity
Expressed in the corneal epithelium (at protein level).
Target Synonyms
CK-12; Cytokeratin-12; K12; K1C12_HUMAN; Keratin 12; Keratin; Keratin; type I cytoskeletal 12; Keratin-12; KRT12; type I cytoskeletal 12
Target Background
KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Mutations in this gene lead to Meesmann corneal dystrophy.
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