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| Cat.No | ACP22805 | Target Name | KIF11 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P52732 |
|---|
Uniprot Id
P52732
Target Species
Human
Target Name
KIF11
Target Full Name
Kinesin-like protein KIF11
Target Function
Motor protein required for establishing a bipolar spindle during mitosis. Required in non-mitotic cells for transport of secretory proteins from the Golgi complex to the cell surface.
Target Involvement
Microcephaly with or without chorioretinopathy, lymphedema, or mental retardation (MCLMR)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, spindle pole.
Target Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family, BimC subfamily
Target Synonyms
EG5; HKSP; KIF11; KIF11_HUMAN; Kinesin family member 11; Kinesin like protein 1; Kinesin-like protein 1; Kinesin-like protein KIF11; Kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; KNSL1; MCLMR; Thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP-5; TRIP5
Target Background
This gene encodes a motor protein that belongs to the kinesin-like protein family. Members of this protein family are known to be involved in various kinds of spindle dynamics. The function of this gene product includes chromosome positioning, centrosome separation and establishing a bipolar spindle during cell mitosis.
Notification