Recombinant Human Kinesin-like protein KIF13A (KIF13A), Truncated

Cat.No	ACP11010	Target Name	KIF13A
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP11010

Target Name

KIF13A

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q9H1H9

Background Information

Uniprot Id

Q9H1H9
Target Species

Human
Target Name

KIF13A
Target Full Name

Kinesin-like protein KIF13A
Target Function

Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recycling endosomal subdomains in melanocytes. Also required for the abcission step in cytokinesis: mediates translocation of ZFYVE26, and possibly TTC19, to the midbody during cytokinesis.
Target Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Midbody. Endosome membrane. Golgi apparatus membrane. Note=Recruited to the midbody during cytokinesis.
Target Protein Families

TRAFAC class myosin-kinesin ATPase superfamily, Kinesin family
Target Tissue Specificity

Widely expressed, with highest levels in heart, brain and skeletal muscle.
Target Synonyms

bA500C11.2 ; FLJ27232; Homolog of mouse KIF13A mannose 6 phosphate receptor transporter; KI13A_HUMAN; KIF 13A; Kif13a; Kinesin family member 13A; Kinesin like protein KIF13A; Kinesin like protein RBKIN ; Kinesin-like protein KIF13A; Kinesin-like protein RBKIN; RBKIN
Target Background

This gene encodes a member of the kinesin family of microtubule-based motor proteins that function in the positioning of endosomes. This family member can direct mannose-6-phosphate receptor-containing vesicles from the trans-Golgi network to the plasma membrane, and it is necessary for the steady-state distribution of late endosomes/lysosomes. It is also required for the translocation of FYVE-CENT and TTC19 from the centrosome to the midbody during cytokinesis, and it plays a role in melanosome maturation. Alternative splicing of this gene results in multiple transcript variants.

Recombinant Human Kinesin-like protein KIF13A (KIF13A), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Kinesin-like protein KIF13A (KIF13A), Truncated Now

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