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Amino acids 1-113 constitute the expression domain of recombinant Human CT83. This CT83 protein is expected to have a theoretical molecular weight of 26.8 kDa. This CT83 recombinant protein is manufactured in e.coli. Fusion of the N-terminal 6xHis-B2M tag into the CT83 encoding gene fragment was conducted, allowing for easier detection and purification of the CT83 protein in subsequent stages.Human kita-Kyushu lung cancer antigen 1 (CT83) is a cancer-testis antigen implicated in tumorigenesis. CT83 is overexpressed in various cancers, particularly lung cancer. Investigation of CT83 provides insights into cancer biology, immunotherapy targets, and potential applications in cancer prognostics, and therapeutic strategies. In cancer research, CT83 is a potential biomarker for prognosis. Its role in immune responses makes it relevant in immunotherapy research. Additionally, CT83's involvement in tumor cell proliferation and survival suggests its contribution to oncogenic processes.
Amino acids 1-113 constitute the expression domain of recombinant Human CT83. This CT83 protein is expected to have a theoretical molecular weight of 26.8 kDa. This CT83 recombinant protein is manufactured in e.coli. Fusion of the N-terminal 6xHis-B2M tag into the CT83 encoding gene fragment was conducted, allowing for easier detection and purification of the CT83 protein in subsequent stages.Human kita-Kyushu lung cancer antigen 1 (CT83) is a cancer-testis antigen implicated in tumorigenesis. CT83 is overexpressed in various cancers, particularly lung cancer. Investigation of CT83 provides insights into cancer biology, immunotherapy targets, and potential applications in cancer prognostics, and therapeutic strategies. In cancer research, CT83 is a potential biomarker for prognosis. Its role in immune responses makes it relevant in immunotherapy research. Additionally, CT83’s involvement in tumor cell proliferation and survival suggests its contribution to oncogenic processes.
| Cat.No | ACP02436 | Target Name | CT83 |
|---|---|---|---|
| Target Synonyms | CT83; CXorf61; KKLC1; Kita-kyushu lung cancer antigen 1; KK-LC-1; Cancer/testis antigen 83 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-113aa |
| Mol Weight | 26.8kDa | Protein Length | Full length |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5H943 |
|---|
Uniprot Id
Q5H943
Target Species
Human
Target Name
CT83
Target Full Name
Kita-kyushu lung cancer antigen 1
Target Subcellular Location
Cell membrane; Single-pass type II membrane protein.
Target Tissue Specificity
Specifically expressed in testis. Expressed by cancer cell lines.
Target Research Area
Cancer
Target Synonyms
CT83; CXorf61; KKLC1; Kita-kyushu lung cancer antigen 1; KK-LC-1; Cancer/testis antigen 83
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