Home Products Recombinant Human Krueppel-like factor 12 (KLF12)

Recombinant Human Krueppel-like factor 12 (KLF12)

ACP09492

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Specifications

Cat.No	ACP09492	Target Name	KLF12
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-402	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9Y4X4

Background Information

Uniprot Id

Q9Y4X4
Target Species

Human
Target Name

KLF12
Target Full Name

Krueppel-like factor 12
Target Function

Confers strong transcriptional repression to the AP-2-alpha gene. Binds to a regulatory element (A32) in the AP-2-alpha gene promoter.
Target Subcellular Location

Nucleus.
Target Protein Families

Sp1 C2H2-type zinc-finger protein family
Target Synonyms

2700063E05Rik; AI225908; AI315654; AP-2 repressor; AP-2rep; AP-2rep transcription factor; AP2REP; B130052C06Rik; D530033K05Rik; HSPC122; KLF12; KLF12 zinc finger transcriptional repressor; KLF12_HUMAN; Krueppel like factor 12; Krueppel-like factor 12; OTTHUMP00000018503; Transcriptional repressor AP 2rep ; Transcriptional repressor AP-2rep
Target Background

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.

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Recombinant Human Krueppel-like factor 12 (KLF12)

Specifications

Immunogen Information

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