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Recombinant Human Krueppel-like factor 17 (KLF17)

ACP17325

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Specifications

Cat.No	ACP17325	Target Name	KLF17
Target Synonyms	FLJ40160; KLF17; KLF17_HUMAN; Krueppel like factor 17; Krueppel-like factor 17; Novel zinc finger protein; RP4 675G8.1; RP4675G8.1; Zfp393; Zinc finger protein 393; ZNF393	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-389
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q5JT82

Background Information

Uniprot Id

Q5JT82
Target Species

Human
Target Name

KLF17
Target Full Name

Krueppel-like factor 17
Target Function

Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5'-CACCC-3' sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
Target Subcellular Location

Nucleus.
Target Protein Families

Sp1 C2H2-type zinc-finger protein family
Target Synonyms

FLJ40160; KLF17; KLF17_HUMAN; Krueppel like factor 17; Krueppel-like factor 17; Novel zinc finger protein; RP4 675G8.1; RP4675G8.1; Zfp393; Zinc finger protein 393; ZNF393
Target Background

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within gamete generation. Predicted to be located in nucleus. Predicted to be part of chromatin.

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Recombinant Human Krueppel-like factor 17 (KLF17)

Specifications

Immunogen Information

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