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| Cat.No | ACP10445 | Target Name | LARP6 |
|---|---|---|---|
| Target Synonyms | Acheron; Achn; FLJ11196; La ribonucleoprotein domain family member 6; La-related protein 6; LARP6; LARP6_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-491 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BRS8 |
|---|
Uniprot Id
Q9BRS8
Target Species
Human
Target Name
LARP6
Target Full Name
La-related protein 6
Target Function
Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.
Target Subcellular Location
Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm.
Target Tissue Specificity
Expressed in numerous tissues.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Acheron; Achn; FLJ11196; La ribonucleoprotein domain family member 6; La-related protein 6; LARP6; LARP6_HUMAN
Target Background
Enables RNA binding activity and myosin binding activity. Involved in positive regulation of collagen biosynthetic process; positive regulation of mRNA binding activity; and positive regulation of translation. Located in nucleus. Part of polysome.
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