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| Cat.No | ACP14373 | Target Name | LRR1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-414 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96L50 |
|---|
Uniprot Id
Q96L50
Target Species
Human
Target Name
LRR1
Target Full Name
Leucine-rich repeat protein 1
Target Function
May negatively regulate the 4-1BB-mediated signaling cascades which result in the activation of NK-kappaB and JNK1. Probable substrate recognition subunit of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Target Tissue Specificity
Ubiquitous. Maximal expression was seen in the heart and skeletal muscle and minimal expression seen in the kidney.
Target Synonyms
4 1BB mediated signaling molecule; 4 1BBlrr ; 4-1BB-mediated-signaling molecule; 4-1BBlrr; Cyclophilin like 5; Leucine-rich repeat protein 1; LLR1_HUMAN; LRR 1; LRR repeat protein 1; LRR-1; LRR-repeat protein 1; LRR1; MGC20689; peptidylprolyl isomerase (cyclophilin) like 5; Peptidylprolyl isomerase like 5; Peptidylprolyl isomerase-like 5; PPIL5
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