Recombinant Human Liprin-beta-1 (PPFIBP1), Truncated

Cat.No	ACP15625	Target Name	PPFIBP1
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP15625

Target Name

PPFIBP1

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q86W92

Background Information

Uniprot Id

Q86W92
Target Species

Human
Target Name

PPFIBP1
Target Full Name

Liprin-beta-1
Target Function

May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.
Target Protein Families

Liprin family, Liprin-beta subfamily
Target Tissue Specificity

Widely expressed. Absent in liver.
Target Synonyms

PPFIBP 1; hSGT2; hSgt2p; KIAA1230; L2; LIPB1_HUMAN; Liprin beta 1; liprin related protein; Liprin-beta-1; PPFIBP1; Protein tyrosine phosphatase receptor type f polypeptide interacting protein binding protein 1; Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1; PTPRF interacting protein binding protein 1; PTPRF interacting protein; binding protein 1 (liprin beta 1); PTPRF-interacting protein-binding protein 1; SGT2
Target Background

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Recombinant Human Liprin-beta-1 (PPFIBP1), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Liprin-beta-1 (PPFIBP1), Truncated Now

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