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| Cat.No | ACP14528 | Target Name | LYPD6B |
|---|---|---|---|
| Target Synonyms | LYPD6BLy6/PLAUR domain-containing protein 6B | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 40-164 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NI32 |
|---|
Uniprot Id
Q8NI32
Target Species
Human
Target Name
LYPD6B
Target Full Name
Ly6/PLAUR domain-containing protein 6B
Target Function
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Synonyms
LYPD6BLy6/PLAUR domain-containing protein 6B
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