Recombinant Human Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (MCAT)

Uniprot Id

Q8IVS2

Target Species

Human

Target Name

MCAT

Target Full Name

Malonyl-CoA-acyl carrier protein transacylase, mitochondrial

Target Function

Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondria.

Target Subcellular Location

Mitochondrion.

Target Protein Families

Type II malonyltransferase family

Target Synonyms

[Acyl-carrier-protein] malonyltransferase; FabD; FABD_HUMAN; FASN 2C; FASN2C; Malonyl CoA acyl carrier protein transacylase; Malonyl CoA acyl carrier protein transacylase mitochondrial; Malonyl CoA:ACP acyltransferase (mitochondrial); Malonyl CoA:ACP acyltransferase; Malonyl CoA:acyl carrier protein transacylase mitochondrial; Malonyl-CoA-acyl carrier protein transacylase; Mcat; MCT; MCT1; MGC47838; mitochondrial; Mitochondrial malonyl CoA:ACP acyltransferase; Mitochondrial malonyltransferase; NET62

Target Background

The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms.