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| Cat.No | ACP20352 | Target Name | MBLAC1 |
|---|---|---|---|
| Target Synonyms | MBLAC1; Metallo-beta-lactamase domain-containing protein 1; EC 3.-.-.- | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-266 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | A4D2B0 |
|---|
Uniprot Id
A4D2B0
Target Species
Human
Target Name
MBLAC1
Target Full Name
Metallo-beta-lactamase domain-containing protein 1
Target Function
Endoribonuclease that catalyzes the hydrolysis of histone-coding pre-mRNA 3'-end. Involved in histone pre-mRNA processing during the S-phase of the cell cycle, which is required for entering/progressing through S-phase. Cleaves histone pre-mRNA at a major and a minor cleavage site after the 5'-ACCCA-3' and the 5'-ACCCACA-3' sequence, respectively, and located downstream of the stem-loop. May require the presence of the HDE element located at the histone pre-RNA 3'-end to avoid non-specific cleavage.
Target Subcellular Location
Cytoplasm, cytosol. Nucleus.
Target Protein Families
Metallo-beta-lactamase superfamily, Glyoxalase II family
Target Synonyms
MBLAC1; Metallo-beta-lactamase domain-containing protein 1; EC 3.-.-.-
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