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| Cat.No | ACP10258 | Target Name | MRGBP |
|---|---|---|---|
| Target Synonyms | MRGBP; C20orf20; MRG/MORF4L-binding protein; MRG-binding protein; Up-regulated in colon cancer 4; Urcc4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-204 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NV56 |
|---|
Uniprot Id
Q9NV56
Target Species
Human
Target Name
MRGBP
Target Full Name
MRG/MORF4L-binding protein
Target Function
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage
Target Subcellular Location
Nucleus.
Target Protein Families
EAF7 family
Target Synonyms
MRGBP; C20orf20; MRG/MORF4L-binding protein; MRG-binding protein; Up-regulated in colon cancer 4; Urcc4
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