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Recombinant Human Multicilin (MCI)

ACP19767

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP19767 Target NameMCIDAS
Target SynonymsIDAS; Mci; MCI_HUMAN; Multicilin; Protein IdasFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-385
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDD6RGH6
Background Information
  • Uniprot Id

    D6RGH6

  • Target Species

    Human

  • Target Name

    MCIDAS

  • Target Full Name

    Multicilin

  • Target Function

    Transcription regulator specifically required for multiciliate cell differentiation. Acts in a multiprotein complex containing E2F4 and E2F5 that binds and activates genes required for centriole biogenesis. Required for the deuterosome-mediated acentriolar pathway. Plays a role in mitotic cell cycle progression by promoting cell cycle exit. Modulates GMNN activity by reducing its affinity for CDT1.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Geminin family

  • Target Synonyms

    IDAS; Mci; MCI_HUMAN; Multicilin; Protein Idas

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