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| Cat.No | ACP20988 | Target Name | LSM8 |
|---|---|---|---|
| Target Synonyms | LSM8U6 snRNA-associated Sm-like protein LSm8 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-96 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95777 |
|---|
Uniprot Id
O95777
Target Species
Human
Target Name
LSM8
Target Full Name
U6 snRNA-associated Sm-like protein LSm8
Target Function
Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
Target Subcellular Location
Nucleus.
Target Protein Families
SnRNP Sm proteins family
Target Synonyms
LSM8U6 snRNA-associated Sm-like protein LSm8
Target Background
This gene encodes a member of the like-Sm family of proteins. The encoded protein consists of a closed barrel shape, made up of five anti-parallel beta strands and an alpha helix. This protein partners with six paralogs to form a heteroheptameric ring which transiently binds U6 small nuclear RNAs and is involved in the general maturation of RNA in the nucleus.
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