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| Cat.No | ACP10222 | Target Name | NDUFAF4 |
|---|---|---|---|
| Target Synonyms | C6orf66; Hormone-regulated proliferation-associated protein of 20 kDa; HRPAP20; HSPC125; My013; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4; NDUF4_HUMAN; Ndufaf4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-175 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9P032 |
|---|
Uniprot Id
Q9P032
Target Species
Human
Target Name
NDUFAF4
Target Full Name
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
Target Function
Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion.
Target Involvement
Mitochondrial complex I deficiency (MT-C1D)
Target Subcellular Location
Mitochondrion. Membrane; Lipid-anchor.
Target Protein Families
NDUFAF4 family
Target Synonyms
C6orf66; Hormone-regulated proliferation-associated protein of 20 kDa; HRPAP20; HSPC125; My013; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4; NDUF4_HUMAN; Ndufaf4
Target Background
NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency.
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