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| Cat.No | ACP22636 | Target Name | NANOS3 |
|---|---|---|---|
| Target Synonyms | NANO3_HUMAN; Nanos homolog 3; NANOS3; NOS-3; Nos3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-173 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P60323 |
|---|
Uniprot Id
P60323
Target Species
Human
Target Name
NANOS3
Target Full Name
Nanos homolog 3
Target Function
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.
Target Subcellular Location
Nucleus. Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, P-body.
Target Protein Families
Nanos family
Target Tissue Specificity
Ovary, testis and brain (at protein level). In the ovaries, expressed during multiple stages of oogenesis, including primordial, primary, secondary and antral follicles with the highest expression in the oocytes. In the testis, expressed in germ cells, ty
Target Synonyms
NANO3_HUMAN; Nanos homolog 3; NANOS3; NOS-3; Nos3
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