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| Cat.No | ACP11701 | Target Name | CALY |
|---|---|---|---|
| Target Synonyms | CALCYON; Caly; CALY_HUMAN; D1 dopamine receptor interacting protein; Drd1ip; Neuron specific vesicular protein calcyon; Neuron-specific vesicular protein calcyon; NSG3; RP11-122K13.5 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NYX4 |
|---|
Uniprot Id
Q9NYX4
Target Species
Human
Target Name
CALY
Target Full Name
Neuron-specific vesicular protein calcyon
Target Function
Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.
Target Subcellular Location
Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.
Target Protein Families
NSG family
Target Tissue Specificity
Expressed in the pyramidal cells of the prefrontal cortex, in hippothalamus and in caudate nucleus. No expression in spleen. Up-regulated in the prefrontal cortex of schizophrenic patients with nearly twice the levels of non-schizophrenics.
Target Synonyms
CALCYON; Caly; CALY_HUMAN; D1 dopamine receptor interacting protein; Drd1ip; Neuron specific vesicular protein calcyon; Neuron-specific vesicular protein calcyon; NSG3; RP11-122K13.5
Target Background
The protein encoded by this gene is a type II single transmembrane protein. It is required for maximal stimulated calcium release after stimulation of purinergic or muscarinic but not beta-adrenergic receptors. The encoded protein interacts with D1 dopamine receptor and may interact with other DA receptor subtypes and/or GPCRs.
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