Recombinant Human Neurotensin/neuromedin N (NTS), Truncated

Uniprot Id

P30990

Target Species

Human

Target Name

NTS

Target Full Name

Neurotensin/neuromedin N

Target Function

Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle.

Target Subcellular Location

Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Packaged within secretory vesicles.

Target Protein Families

Neurotensin family

Target Research Area

Neuroscience

Target Synonyms

Human proneurotensin; Large neuromedin N; Neuromedin N preproprotein; Neurotensin/neuromedin N; NEUT_HUMAN; NMN 125; NmN; NmN-125; NN; NT; NT/N; NTRH; NTS; NTS1; Pro neurotensin/neuromedin; Proneuromedin N mRNA; Tail peptide

Target Background

This gene encodes a common precursor for two peptides, neuromedin N and neurotensin. Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Neurotensin also exhibits antimicrobial activity against bacteria and fungi. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptides that are also biologically active.