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Recombinant Human Olfactomedin-like protein 3 (OLFML3)

ACP10581

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP10581 Target NameOLFML3
Target SynonymsHNOEL-iso; hOLF44; OLF44; Olfactomedin like 3; Olfactomedin-like protein 3; OLFL3_HUMAN; OLFML3FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range22-406
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9NRN5
Background Information
  • Uniprot Id

    Q9NRN5

  • Target Species

    Human

  • Target Name

    OLFML3

  • Target Full Name

    Olfactomedin-like protein 3

  • Target Function

    Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation. May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    OLFML3 family

  • Target Tissue Specificity

    Abundant in placenta, moderate in liver and heart, whereas fairly weak in other tissues examined. On term placenta, mainly localized extracellularly surrounding the syncytiotrophoblastic cells and very rarely expressed in the maternal decidua layer.

  • Target Synonyms

    HNOEL-iso; hOLF44; OLF44; Olfactomedin like 3; Olfactomedin-like protein 3; OLFL3_HUMAN; OLFML3

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