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| Cat.No | ACP19658 | Target Name | RNF219 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-726 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5W0B1 |
|---|
Uniprot Id
Q5W0B1
Target Species
Human
Target Name
OBI1
Target Full Name
ORC ubiquitin ligase 1
Target Function
E3 ubiquitin ligase essential for DNA replication origin activation during S phase. Acts as a replication origin selector which selects the origins to be fired and catalyzes the multi-mono-ubiquitination of a subset of chromatin-bound ORC3 and ORC5 during S-phase.
Target Subcellular Location
Chromosome.
Target Research Area
Others
Target Synonyms
2610206B13Rik; 2810449K13Rik; AI451544; DKFZp686A01276; DKFZp686N15250; DKFZp686O03173; FLJ13449; FLJ25774; MGC35679; RGD1564706; RING finger protein 219; RING finger protein C13orf7; RN219_HUMAN; RNF219
Target Background
Enables chromatin binding activity and ubiquitin-protein transferase activity. Involved in protein autoubiquitination; protein monoubiquitination; and regulation of DNA replication. Located in chromatin.
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