Home Products Proteins Recombinant Proteins Recombinant Human Paired amphipathic helix protein Sin3b (SIN3B), Truncated

Recombinant Human Paired amphipathic helix protein Sin3b (SIN3B), Truncated

ACP20740

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Specifications

Cat.No	ACP20740	Target Name	SIN3B
Target Synonyms	SIN3B; KIAA0700; Paired amphipathic helix protein Sin3b; Histone deacetylase complex subunit Sin3b; Transcriptional corepressor Sin3b	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	O75182

Background Information

Uniprot Id

O75182
Target Species

Human
Target Name

SIN3B
Target Full Name

Paired amphipathic helix protein Sin3b
Target Function

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription. With FOXK1, regulates cell cycle progression probably by repressing cell cycle inhibitor genes expression.
Target Subcellular Location

Nucleus.
Target Synonyms

SIN3B; KIAA0700; Paired amphipathic helix protein Sin3b; Histone deacetylase complex subunit Sin3b; Transcriptional corepressor Sin3b
Target Background

Predicted to enable transcription corepressor activity. Predicted to be involved in histone deacetylation; negative regulation of transcription by RNA polymerase II; and striated muscle tissue development. Predicted to be located in nucleus. Predicted to be part of Sin3 complex. Predicted to be active in chromatin.

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Recombinant Human Paired amphipathic helix protein Sin3b (SIN3B), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Paired amphipathic helix protein Sin3b (SIN3B), Truncated Now

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