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| Cat.No | ACP23562 | Target Name | PTX3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 18-381 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P26022 |
|---|
Uniprot Id
P26022
Target Species
Human
Target Name
PTX3
Target Full Name
Pentraxin-related protein PTX3
Target Function
Plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility.
Target Subcellular Location
Secreted.
Target Synonyms
AI607804; Pentaxin 3; Pentaxin-related protein PTX3; Pentraxin 3 long; Pentraxin-related gene; Pentraxin-related gene rapidly induced by IL-1 beta; Pentraxin-related protein PTX3; PTX3; PTX3_HUMAN; TNF alpha-induced protein 5; TNFAIP5; TSG-14; TSG14; Tumor necrosis factor alpha-induced protein 5; Tumor necrosis factor-inducible gene 14 protein; Tumor necrosis factor-inducible protein TSG-14
Target Background
This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions.
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