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| Cat.No | ACP07051 | Target Name | PRPH2 |
|---|---|---|---|
| Target Synonyms | PRPH2; PRPH; RDS; TSPAN22; Peripherin-2; Retinal degeneration slow protein; Tetraspanin-22; Tspan-22 | Form | Liquid or Lyophilized powder |
| Expression System | Yeast | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P23942 |
|---|
Uniprot Id
P23942
Target Species
Human
Target Name
PRPH2
Target Full Name
Peripherin-2
Target Function
Essential for retina photoreceptor outer segment disk morphogenesis, may also play a role with ROM1 in the maintenance of outer segment disk structure. Required for the maintenance of retinal outer nuclear layer thickness. Required for the correct development and organization of the photoreceptor inner segment.
Target Involvement
Retinitis pigmentosa 7 (RP7); Retinitis punctata albescens (RPA); Macular dystrophy, vitelliform, 3 (VMD3); Macular dystrophy, patterned, 1 (MDPT1); Choroidal dystrophy, central areolar 2 (CACD2)
Target Subcellular Location
Membrane; Multi-pass membrane protein. Cell projection, cilium, photoreceptor outer segment. Photoreceptor inner segment.
Target Protein Families
PRPH2/ROM1 family
Target Tissue Specificity
Retina (photoreceptor). In rim region of ROS (rod outer segment) disks.
Target Synonyms
PRPH2; PRPH; RDS; TSPAN22; Peripherin-2; Retinal degeneration slow protein; Tetraspanin-22; Tspan-22
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