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| Cat.No | ACP24540 | Target Name | PITPNA |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-270 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q00169 |
|---|
Uniprot Id
Q00169
Target Species
Human
Target Name
PITPNA
Target Full Name
Phosphatidylinositol transfer protein alpha isoform
Target Function
Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions. Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
PtdIns transfer protein family, PI transfer class I subfamily
Target Synonyms
MGC99649; Phosphatidylinositol transfer protein alpha; Phosphatidylinositol transfer protein alpha isoform; Phosphotidylinositol transfer protein; PI-TP-alpha; PIPNA_HUMAN; PITP alpha; Pitpna; PITPNB; PtdIns transfer protein alpha; PtdInsTP alpha; PtdInsTP; Vb; VIB1A; Vibrator
Target Background
This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3, 4, 5-trisphosphate (PIP3) by phosphoinositide-3-kinase.
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