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Recombinant Human Phosphatidylinositol transfer protein alpha isoform (PITPNA)

ACP24540

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP24540 Target NamePITPNA
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range2-270Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ00169
Background Information
  • Uniprot Id

    Q00169

  • Target Species

    Human

  • Target Name

    PITPNA

  • Target Full Name

    Phosphatidylinositol transfer protein alpha isoform

  • Target Function

    Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes. Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions. Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    PtdIns transfer protein family, PI transfer class I subfamily

  • Target Synonyms

    MGC99649; Phosphatidylinositol transfer protein alpha; Phosphatidylinositol transfer protein alpha isoform; Phosphotidylinositol transfer protein; PI-TP-alpha; PIPNA_HUMAN; PITP alpha; Pitpna; PITPNB; PtdIns transfer protein alpha; PtdInsTP alpha; PtdInsTP; Vb; VIB1A; Vibrator

  • Target Background

    This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3, 4, 5-trisphosphate (PIP3) by phosphoinositide-3-kinase.

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